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Multiple Choice

SSRI refers to which pharmacologic class?

SSRI stands for Selective Serotonin Reuptake Inhibitor, a class of antidepressants that selectively blocks the serotonin transporter (SERT), increasing serotonin levels in the synaptic cleft. This selectivity for serotonin reuptake (as opposed to affecting other monoamines) is what defines the acronym. The other terms describe a sleep stage concept, a pharmacokinetic parameter, and a physiological measurement, none of which refer to a drug class. Thus, the correct concept is a pharmacologic class that elevates serotonin by inhibiting its reuptake.

SSRI stands for Selective Serotonin Reuptake Inhibitor, a class of antidepressants that selectively blocks the serotonin transporter (SERT), increasing serotonin levels in the synaptic cleft. This selectivity for serotonin reuptake (as opposed to affecting other monoamines) is what defines the acronym. The other terms describe a sleep stage concept, a pharmacokinetic parameter, and a physiological measurement, none of which refer to a drug class. Thus, the correct concept is a pharmacologic class that elevates serotonin by inhibiting its reuptake.